SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d163e591fb90838b2f4ff39611cec00fe1cf87310012d13c572d5cfd24d8d6e' 
  AND token = 'j+SC083UffcyCkPv5l0zXmLIayWq3uZqP481weae3ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}