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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb9882c595df8f616782e4f9eca3059e2ebddbd1aa7d7c4b81f21f27032c6e5' 
  AND token = 'mydZ1ZepAsLUjYAr8lzMTpZML4mKwlrhdeMmrcUXD48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}