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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217686440075100e43190eaa80440720c29d39d29539f1e51b5dab70a04270d4' 
  AND token = 'Rq+r5W+ARV1C4yzbWNcL8M/YBUagoemav99m6zpsaqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}