SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b53c492ee78f7050768dfb7cbdd3451e5a41dbbf8d63efeba98445898349e7' 
  AND token = 'mAS3BTeOJbd5tYs0foYOi3oi4X5eDQlmw8gmaR9vXgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}