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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccc1635adfc6868978c4903e688d3502d4b12bb57d0e5a3eaaa983a4b55a641' 
  AND token = 'fiqnjtwNp9DzrZ8mkJyRfi+W16LbjfGjDNwy/oiRyGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}