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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff072f6d8d972a7eef4dc391540a53b064e38397730ba5c800cab09e213faf8' 
  AND token = 'zRtqFZ7D+n4r13G6EV4iLgyOOhkwGdLe+bWD2ZYSjyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}