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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5919cbf73d4e8fed2b326e6afd7981ffc6d553f51b129267aea535691afeb55d' 
  AND token = '8H54uOUMOsKH+jCV9BLFQ2ykOQDMPT2Ccwz01p/2yHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}