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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8507bb080a160a313f8f81ce0d6669e4c216f3e0f5e018efb00081d7ac0752' 
  AND token = 'USwHHb0f/WkhzaBGJ6bp4AzQUd0rpY2xeHVCEMTJGf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}