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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f57c19e1f61bd750d9d40552777d51071263df913feed4f07a2613b387628b' 
  AND token = '4R2U7Do4yOd1HNm1lJfT2uNtc3h4SLdJbPm5Lji1Hp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}