SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bb45035b6c904886580cedf136640c71c0dc29d4fbfe17486a2fccfade44c2' 
  AND token = 'xhoMiLyioIflTgwgDoE+nRpAGAYLQGPYCYGo2N7VjnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}