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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7648474e8e545ba1d8ab023d5088512162e2801e5ab4ae2283342be4210a71d8' 
  AND token = 'Iiw+IjDpzY+tujXtygMxGkHZ20T1JxaBn4S6EineujY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}