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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e351648ea08eda5a240e435dab2ea2db7de8d03d4eacee8fb810352da76e122' 
  AND token = 'TWgsGyiEpEsgZ2j/jeGYuLB0bxSnmjeXKUp+VigdmeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00089

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}