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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '214e46f009824b4cf9cc2dc159cd3b591408039f93e9637371b1efcf842de205' 
  AND token = '8EeG/YcobAXC32qBu19fp+/SqlVOzN/FlryeCJXRshI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}