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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83e81b6f2bb1ad86c84ced95b5e0189e789b76c0a3944084e6eda02688c63941' 
  AND token = 'NbUz+R1vWFGAd6DQOk0cMxV6uQ0oMx/NId2V2o7nAi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}