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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b563b6eb19dfc0a02782ffd04e8fb6b3f9c0086feeff3369f3a7309a74af0a4' 
  AND token = 'lMcVJYeJHxwPxN8vDihtJ/fb+OFIdVd1TU+I4ukLIyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}