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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cf3f58c5cda19874ceb3eaa105353f1a05a50bef9785b327afe6a70519c516' 
  AND token = 'IL4jA2Bg/YyFf6CPBbrghJ1shOOV9I+F+T/fi4/b7Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}