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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6301460e5a4d689bd2c567b6e2fa12f08a488e6aecdcfeba06ca1f9720c0cbd8' 
  AND token = '7/hMO9XaFf8mj2XRodz1b4i4bRbcwFETBtwaJkjlmKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}