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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381cb5cb7d401b5e122186b7b0caf7c618a5ab816d283a87f9b6a15317fa9f08' 
  AND token = '22IAv3vRZ8bgdn/aWveNxToIKmVNzv0UClh3YDNHuvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}