SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f301ea06fcc7b5eeaa06baad2fdc01dbd93236131f8917059b54ce4bfd544a2' 
  AND token = 'rTVA8tfA4vvLtaADSpYFJApIk1ulQiyGpokZ37QlOz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}