SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1571b6ba506c783e2d020bff06db77f8ef9595256f54b0380c6123ece3c304' 
  AND token = 'Nn3mlDFiaaVUfdbFFPQYul2MSGOe0X7LHm4hNr3ewqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}