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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a459f4e4af636431698fd2132517901dc5369b480f4f7d82987998f4be14fbb5' 
  AND token = 'tr9XLTYP3IOWvoNAY0mtyx5iDDgQZ3D0+TslCPsjGRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}