SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b92a37417a3fe8987301feda191215b2f275e5ce3ed1861f913c0dc0aa2e723' 
  AND token = 'LLscZ+2TNyMvdcRkdo1ZwGirD3iCaUpJgbn5GxIyTu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}