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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa9fc0014e9a07b714000c18f2f80c705681a2a5011a9799d0a90c6dba16837' 
  AND token = 'KO8s5PtLIS4iFOH9wtJvQTmjAkWp7OnHS1MnBZv52Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}