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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a1c1013f71dd4647f3a6dc31c21e8db2425d0782745b08742ccebf250e22c1' 
  AND token = 'RWVKbKnOaqfX4RQF/kkGr4s2oysC+15ukegzbQIHybU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}