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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b8e0f0ad82d6b1269ce278b0c9e185ddd1517d5eac060c6b341c149bec8fcc' 
  AND token = 'ZmDIOSNLsyyelLtP6Hn6yBrmdZAJWT22fwZYMQTqO04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}