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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c139c46001eca6dbb648607c918a9a645e70c6144455d6fa847f7b7aaaf3a74' 
  AND token = 'mLmJYD3bzMi1OFics4oqzRPdco3FGL9AHWy25euIJCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}