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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e3bd4fe768c686560ff159c6062fbce385e2738379fae8c17e12fa85445585' 
  AND token = 'z1gn8cxrAsHbOJWO+dyD8jg83Fi05FywKoSC8Su+YTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}