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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be22f171628bf8c4225ac9650cd4ca4997bd6f6c7c4f305cdc2ae8d0057ac12' 
  AND token = '9F6sYclK4qvgS0CdoM9o1veI8w+MUgtcznY65FEfDcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}