SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d11b1ba28b64917c8fa4ea38859e4edc818bc004ce2251adc0b07a1317a2a5f' 
  AND token = '7nbR6Wdx2kKR1d2bfvuBAhDFsAaZFFxgSlFRTF7sDBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}