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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da58408c2be55fd78d89bebd0326c112e0a4e2ddd5c52842d460dbab461db057' 
  AND token = 'PDl68+sTKBsQeUCWrr8nFCpYfWOifZda62Nwgw0UpzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}