SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81676df8ce5b72990c3b9b5e1d2c08ed282bf070176b5f76418209d1abd3c668' 
  AND token = 'B2TNKMzQCEKECFwqvHvNgtCrWBskMgn25vy6NucLcwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}