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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301050d53677cf37f6b7f0b64f421dfffe9a56c92fd920d392f749fc0269ec5a' 
  AND token = 'M5/ko+nAa2yaqT1MWUaLPbmw6Pnw5GHSGMznxs97qBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}