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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ea47899e9a21a47f440b3cbe141bd243767a5ea8772a774106e61f9fb2a2a4' 
  AND token = 'hm/o8CKedOYvdh7Xz8dVTjYU6fAk3fYKHvRdnF3tjNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}