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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0a7522b882e2eb3a9add922e56b706a157161e538cbfacde6319ccf769bd7f' 
  AND token = 'cSXtgIPG/P2OHruRresludqRRSWf/uEr4e5WGkWG5Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}