SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cb163c5e2348516e29fed853fe1635275a2bd94e6319183c75183135634bc0' 
  AND token = 'HYCxpKw+xPIY2zgOTuR68Dlj3b99PC9kNJaOd2FM/Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}