SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f18e9bbb3319230e817cdc809a4c229472e977b1724b578a8cf8d892ec46383' 
  AND token = 'XiFNGUCE+EDU1SXkUFeUr/MSXfyxvmtPzdXROGfjMuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}