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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd469a5b92dd3cbe1d5d16a5ef204c84d11c5bc62b6570846ad221678aa1e84d0' 
  AND token = 'cBEZPBzMz3NDeQIjuWPbyNLFpWBcn6ae7FTqm3XlsVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}