SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db4fb758b02282e916303e382ebaecc2b16649b6bb3e0a47bbc273eb1e55388' 
  AND token = 'UmcZajV3noTNdBPfaHrGzr1O2KRLvp5CNAiO9AY7Ke8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}