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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de2aa5f7342081ec28af498ad8a83d74e150bd22225006d50e927179bfbb322' 
  AND token = 'FUiN+iZPhdzjjrDAbDUKgtK1GjBI8tL45Oy3mEW6/bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}