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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e6bc43921027d81e5cd0170afbc68ad2cee496b526297f16b2538f52240749' 
  AND token = '/7zzztTfib/k5HbopdS3ZRjBJtdBr5CfalYh7tx3qSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}