SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ae68d36343b7b2b567021736b0bc5644409e94203be01270d1e8c0e2da4eea' 
  AND token = 'C4SoQ/AwKhM73tSVOtnXI1tb7LG7YPHqVOjLROY2r5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}