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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb77c761a37056a82419ccce72fd2e0bcb0112b3bec786a93e45fb1c8ffca11' 
  AND token = 'd1yxmqS2u5+okm3Kich4wx1GJd9nNpFVPmwTxpDco0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}