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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b0b9b8168a64dcc34e08b62a099a791bd09d89261346453a680a23ad08b302' 
  AND token = 'pxL7krXTO/+Stl2Nb7lVqWFPLpDzc3ClnJmYtgxjRmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}