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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb21fcea7fb52be1961e9976fd661ded5ca8f0214789479f414bd67df56729d7' 
  AND token = '3T7T8pUAhxSMEp5egVRxTUSQvUk+4AUxcdK1/EqIps0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}