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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4980fdcfa73f0f9cadcc9157186a20ae29ed5ddff24ed513b2e5d82377249752' 
  AND token = 'NqwOL3szJHkjdXjyN8sDCJMIqIEAWbpqEQS6sUjWCIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}