SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63ebcdaa950ddcece7fab10ec8b17ed47a7b3264e6c47ac9a193fa00e6adfab6' 
  AND token = 'E8BP3d4islT4N1lufImrxS9p2qvWZeew3rwsNMgAvmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}