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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ee56d6a60a2619584655abc54611d96e95b86a38fdfbed3b9cd5ceb124ca12' 
  AND token = 'LVI7ya/nYr6BEXDbQdApZEHEFhY9EXBIU2Mbi2ytDXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}