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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8c1bb29a2d111195a75ab90315dfaf6f3b129288c1e8596a49b342157a4f98' 
  AND token = 'qqaQw6in2iewipBO34RoroSfbQtmP0y201uBoFtmc6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}