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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1221dc6e7f0058c5db1d192b46263d2eb7f76b80a24f8ac9604814a3aa3d207c' 
  AND token = '3iVbQUsVSILFGpNezOPcAwvNSxVOpTC2Om5CSxf36SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}