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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fab3bda60aa0d9804dac3c08c2b660e6149ad1d5fc2733d689052f81878f2f8' 
  AND token = 'F12RI50WPzripL4ob5EcSsKLmIv4MCU0DhuN3I/9ruk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}